A study on the inhibitory effect of matrine on gastric cancer SGC-7901 cells.
Afr J Tradit Complement Altern Med. 2013;10(6):435-8
Authors: Song S, Zhu S, Zhang Z, Mo Z, Ke Q, Luo Z
The objective of this paper was to investigate the antitumour mechanism of action of matrine by studying its inhibitory effect on gastric cancer SGC-7901 cells. SGC-7901 cells were chosen, and cell-killing capacity of matrine on gastric cancer SGC-7901 cells was determined using MTT assay and single PI staining assay. The results showed that matrine had an inhibitory effect on gastric cancer SGC-7901 cells, which was somewhat dose-dependent. The study concluded that matrine has a significant in-vitro inhibitory effect on SGC-7901 tumour cells, influences cell cycle of SGC-7901 cells, and induces their apoptosis.
PMID: 24311863 [PubMed – indexed for MEDLINE]