Chemoselective derivatization of alkaloids in periwinkle.

Chemoselective derivatization of alkaloids in periwinkle.: Chem Commun (Camb). 2007 Aug 21;(31):3249-51 Authors: Galan MC, McCoy E, O'Connor SE

The terpene indole alkaloid biosynthetic pathway can utilize a secologanin substrate analog containing a handle for functionalization, and the resulting non-natural alkaloids can be chemoselectively derivatized in crude extracts of plant tissue.

PMID: 17668090 [PubMed - indexed for MEDLINE]